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Avanafil (Stendra) was introduced as a medication for erectile dysfunction in 2012 by the FDA and in 2013 by the EMA.

Options for erectile dysfunction medication were always very limited and Avanafil was the first medicine to be launched in over a decade.

When Avanafil hit the market it increased the medications options for erectile dysfunction to five. With so many options available in the market, men started to wonder which one is the best and most effective medicine for treating erectile dysfunction.

There is no definite or fixed answer to this question. Everybody is different, there is no drug that is the best.

Everybody’s chemistry is different than the other, this may make one drug best for one person and another one best for other people. Every drug has its own advantages and disadvantages.

Currently, there are five best Male Enhancement Pills available in the market for erectile dysfunction: Tadalafil, Stendra, Sildenafil, Vardenafil.

What are Oral Erectile Dysfunction Medications?

All the Erectile Dysfunction medications present in the market belong to the same class of drugs: that is, phosphodiesterase type 5 inhibitors, commonly known as PDE-5 inhibitors. PDE-5 inhibitors work by stopping one or more phosphodiesterase enzymes present inside the blood vessels.

By stopping the phosphodiesterase type 5 from working phosphodiesterase type 5 inhibitors cause the blood vessels to relax.

Relaxed blood vessels result in better blood supply to the penis which in turn helps in getting an erection.

These medications can’t work on their own and need a sexual stimulus to active. ED drugs when taken along with sexual stimulation helps is getting an erection sufficient enough to engage in long-lasting sexual intercourse.

Researches and surveys have shown that all the phosphodiesterase type 5 inhibitors work in the same fashion when it comes to efficacy and safety.

But the drugs might differ when it comes to the time of action, how the medication is absorbed with the kind of diet on is taking, the durability of effect, and the kind of side effects the medication causes.

It is these factors that help men in deciding which medication to choose depending on their needs and the kind of lifestyle they are used to. Other factors like the cost of the medication may also fall into consideration.

Apart from these individual factors, men might also consider their partners’ preferences like how spontaneous they are when it comes to sexual intercourse or any other sexual activity.

Some medications start affecting in 30 mins and last up to 4-5 hours, others might take around 60 mins to hit but the effect might last as long as 36 hours.

For example, back in 2011, there was a meta-analysis conducted on the use of three erectile dysfunction medication- tadalafil, vardenafil, sildenafil on around 7700 hundred men.

The analysis showed that around 52-65% of men prefer Tadalafil(Cialis) over Sildenafil(8-30%) and Vardenafil(12-20%)

Although all the three best Male Enhancement Pills are the same when it comes to safety and effect tadalafil gave men a window of 36 hours after ingestion as compared to the other two medications.

That means men had the opportunity to indulge in sexual intercourse for 36 hours after taking the medication as opposed to the other two medications were the effect lasts for only up to 4 hours.

If all the erectile dysfunction medication shows the same effect and are equally safe, choosing a medication that has a longer effect is a wiser choice.

How to compare Erectile Dysfunction drugs?

People who have Erectile Dysfunction can choose one of the five medications they want to take the basis of certain characteristics.

These characteristics coupled with personal preferences, lifestyle, and habits can help them choose the medication that is best suited for them. Here are the five medications with their characteristics:

Avanafil

• Avanafil starts working within 15 mins of taking the tablet. It could take a little longer for some men.
• It can be taken along with food or even without it, the response is not affected in either case.
• The effect lasts for up to 6 hours which means men can get an erection till six hours after taking the medicine.
• Side effects include headache, nausea, runny nose, nasal congestion, and flushing. Some other less common side effects may include dizziness, hypertension, muscle pains, respiratory infections, diarrhoea, and influenza.

Tadalafil

• Tadalafil starts working within 30-45 mins of taking the tablet., although there are some cases reported where the medicine has affected within 15 mins.
• The medicine can be taken with or without food without any effect on its response.
• The effect lasts for up to 36 hours after the pill starts affecting. This means that a man can indulge in sexual intercourse for up to 36 hours after taking the medication.
• The common side effects include headaches and indigestion. Less common side effects include facial flushing, back pains, dizziness, nasal congestion, and muscle aches.  

Levitra and Staxyn

• The medicine starts to kick in within 25 minutes of ingestion but it might take longer depending on the kind of meal taken before taking the medicine. If the last meal taken is fatty then the medicine might take longer to kick in.
• The effect lasts for up to 4 to 5 hours.
• The most common side effects include facial flushing and headaches. Lesser known side effects include dizziness, indigestion, nausea, nasal congestion, and blue-tinged vision.

Sildenafil Citrate

• Starts to work within 30 to 45 mins of consumption
• The time taken to kick in might vary if taken with food. When taken with food, it takes a longer time to kick in.
• The effect lasts for up to 2 to 3 hours although if taken a higher dose like cenforce 100mg, 150mg, 200mg  the effect can last up to 5 hours.
• The most common side effects include compromised vision, back pains, nausea, rash, muscle pains, headache, running nose, flushing, and upset stomach. Lesser known side effects may include irregular heartbeat or a stroke.

Cost of Erectile Dysfunction Drugs

One of the major factors that should be considered while choosing the best ED medication is the price point. Insures mostly limit the number of pills that you can have access to per month(typically four). If one requires more pills then they have to pay for it.

The cost per pill can be as high as $5 to $20. So cost becomes one of the factors while buying ED medication but Generic Villa, we can give trusted and safest best Male Enhancement Pills at an affordable price starting at $0.80 with free shipping worldwide. if you bye safe generic pharmacy visit our official site Genericvilla.com

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Mary Hill Dr. Marry Hill is one of the amongst and best urologists and content writer, who has treated hundreds of USA as well as international patients. She loves to write content based on Men’s Health problems like Erectile Dysfunction and Sexual Disorders. You can connect on Twitter: @maryhil14623979. View all posts by Mary Hill